ResMed’s non-invasive ventilation technologies suitable for COPD

ResMed offers you intelligent non-invasive ventilation solutions that can help you tailor treatment to the unique and changing needs of your patients. From ventilators and masks to oxygen options and accessories, ResMed’s solutions work together to help patients breathe easier as they manage their condition.


Today, on World COPD Day, we are excited to share the results of the HOT-HMV trial presented at ERS, which show that HMV added to HOT can reduce by 51% the likelihood of readmissions to hospital or death over one year in hypercapnic COPD patients following an acute exacerbation of COPD.1 There are new prospects for better treatment of COPD—and better lives for patients.


Excellence in non-invasive ventilation

Successful ventilation relies on improving gas exchange and reducing the work of breathing while keeping the patient comfortable. Maintaining patient-device synchrony and managing leak is critical to achieving this.

Ventilator asynchrony can cause significant discomfort, distress and poor clinical outcomes. One study estimates that 40% of non-invasive ventilation patients experience asynchrony in 10% or more of their breaths.1,2

A good device should help overcome this by:

  • Monitoring and compensating for leak
  • Accurately sensing the start and end of a patient’s inspiratory effort for triggering and cycling
  • Responding quickly to reach and maintain the set pressure
  • Offering flexibility of settings to accommodate pathological variations in the patient’s respiratory timing/pattern

Designed to identify changes to a patient’s breathing, where sensitivity to leak and patient–ventilator asynchrony is important, all our devices feature the following technologies to help you provide better clinical outcomes:

Vsync provides synchrony in the presence of leak

Acutely sensitive to a patient’s breathing, our Vsync algorithm rapidly compensates for any presence of leak by automatically adjusting the baseline flow. And because it can also accurately estimate respiratory flow and tidal volume, it is beneficial for circuits with intentional leak. All this is achieved while maintaining reliable triggering and cycling, and set pressures.


TiControl helps the patient to exhale

TiControl allows clinicians to limit the minimum and maximum amount of inspiratory time to suit a patient’s condition. For COPD patients, whose respiratory flow is restricted, and who have difficulties exhaling, a shortened Ti Max (maximum time a patient can spend in inspiration) can prevent late cycling to expiratory pressure, which helps provide a better match to the patient’s ideal inspiratory time.


Five adjustable levels of trigger and cycle sensitivities

By determining the timing and level of effort at the beginning and end of each breath, you can fine-tune sensitivity settings to match a patient’s spontaneous breath cycle.

For Lumis™ and Astral™ ventilators, the default Medium setting will be appropriate in most cases.

Major therapy parameters can be pre-programmed in some of our ventilators to help you set up. (E.g. By choosing ‘Obstructive Lung’ from the Pathology Defaults for patients with COPD using a Stellar™ ventilator.)

However, having the option to fine-tune trigger and cycle sensitivities allows further customisation at the beginning and end of each inspiration.

This helps reduce the patient’s work of breathing, and optimise patient–ventilator synchrony.


Controllable rise and fall times allow you to optimise the patient’s work of breathing, comfort and synchrony.

Rise time is the time it takes for the ventilator to reach the set inspiratory pressure after triggering; Fall time is the time it takes to reach the set expiratory pressure after cycling.

Rise and fall times can be tailored to suit different individuals and their conditions. Faster rise and fall times ensure rapid transitions, while slower times provide a more gradual transition.

For a COPD patient, a faster rise time setting can help the lungs fill quickly.


As well as the technologies featured above, ResMed’s ventilators provide a range of ventilation modes:

Traditional modes include:

CPAP mode—where a fixed pressure is delivered.

S (Spontaneous) mode—the device senses the patient’s breath and delivers IPAP in response to an increase in flow, and cycles into EPAP at the end of inspiration. The breath rate and respiratory pattern will be determined by the patient’s breathing.

ST (Spontaneous/Timed) or PS (Pressure Support) mode—the device augments any breath initiated by the patient, but will also supply additional breaths should the patient’s breath rate fall below the clinician's set ’backup’ breath rate.

T (Timed) mode—the fixed breath rate and fixed inspiration time set by the clinician are supplied regardless of patient effort.

PAC (Pressure Assist Control)—the inspiration time is pre-set in PAC mode. There is no spontaneous/flow cycling. The inspiration can be triggered by the patient when the respiratory rate is above a pre-set value, or time-triggered breaths will be delivered at the backup breath rate.

ResMed’s iVAPS mode

With the introduction of iVAPS mode, an intelligent back-up rate (iBR), and auto-adjusting AutoEPAP feature, we can help set a new standard in personalised and responsive ventilation for COPD patients. Together, we call these new technologies ‘IntelligentAir’.

iVAPS delivers auto-adjusting pressure support

Targeting each patient’s unique alveolar ventilation, iVAPS mode auto-adjusts the pressure support to maintain that target, and stabilise the patient’s breathing.

iVAPS automatically adapts to the patient’s changing needs by constantly monitoring their actual ventilation and respiratory rate in relation to their target ventilation and respiratory rate.


iBR inserts backup breaths only when needed

A feature of iVAPS, the intelligent Backup Rate (iBR) provides backup breaths only when needed, to allow maximum opportunity for spontaneous breathing.

Giving patients maximum opportunity to spontaneously trigger the ventilator, iBR shifts between two limits: the target patient rate, and its background frequency, which is two-thirds of the target rate.


The importance of targeting alveolar ventilation

Some ventilation modes target tidal volume (or minute ventilation), without taking into account the anatomical dead space in the patient’s airways. What’s different about ResMed’s iVAPS mode is that it targets alveolar ventilation, which represents the most accurate measure of a patient’s lung and respiratory capacity.

Because iVAPS takes into account both tidal volume and respiratory rate, by targeting alveolar ventilation, the effect of respiratory rate variation on ventilatory support can be better controlled.


AutoEPAP addresses upper airway obstructions

Complementing iVAPS, the optional AutoEPAP feature helps address partial and full obstructions to maintain upper airway patency.

AutoEPAP responds to upper airway obstructions by auto-adjusting expiratory pressure according to the severity of the event.


Our comprehensive range of ventilators

Our ventilators are designed with your COPD patients’ quality of life in mind. Patients can feel confident knowing that a ResMed ventilator will keep them supported as they continue with their daily lives in or out of the hospital and home.

ResMed’s non-invasive ventilators have simplicity built into their design, so it’s easy to set up, monitor and change therapy from the ventilator itself.

Easy to use in hospital as well as in patients’ homes, each of our ventilators features menu options that allow ‘low-touch’ therapy setup and adjustment.

ResMed offers three series of ventilators to help COPD patients breathe easier:


A recent addition to the ResMed family, Lumis has an intuitive menu and small footprint. It can give COPD patients comfortable, personalised non-invasive ventilation with warmed, humidified air. Simple to set up and titrate, Lumis synchronises easily with the patient’s breathing. Lumis’ optional Ramp and Ramp down features help patients ease into and out of therapy.

  • Lumis’ QuickNav feature gives you a low-touch solution to therapy adjustment. By simply double-clicking the home button on the device, you can quickly and easily toggle between the Settings screen (where you can adjust your patient’s therapy) and the Monitoring screen (where you can check the impact of those adjustments on the patient’s therapy).
  • Essentials mode caters for patients who want to receive their prescribed therapy without worrying about other settings or menus. They can simply press Start and the ventilator takes care of the rest.
  • Oxygen can be conveniently delivered by the optional ClimateLineAir™ Oxy tube.
  • Humidification is delivered via a built-in humidifier – so your patients can receive all the comfort of humidification as soon as they turn on their device.


Stellar is an invasive and non-invasive ventilator that is designed for versatility. It is suited for patients with changing ventilatory needs and progressive respiratory conditions, including COPD.

  • Patient interface options provide a range of invasive and non-invasive therapy applications for different patient types and conditions.
  • Critical setup options like Learn Circuit and Mask Type are displayed on the first clinical menu screen you see, enabling you to access important settings immediately.
  • Pathology Defaults are pre-set and organised by disease category to provide staff with a helpful starting point from which they can quickly fine-tune (if necessary) to suit the individual patient’s needs.
  • 2 therapy programs allow clinicians to pre-set and store programs for patients with treatment requirements that change under particular conditions (e.g. day/night). This enables quick transitions between therapy settings without manual fine-tuning.
  • Pressure range: 2–40 cmH2O.
  • Real-time graphs and monitored values assist therapy assessment and titration.
  • Encourage patient mobility with battery options providing a total of up to 18 hours of run-time (using the internal battery and 2 additional external batteries).
  • Oxygen is entrained at the back of the device, which can take up to 30 L/min.
  • SpO2 and FiO2 monitoring options are also available.


Astral is a life support ventilator, which can be used invasively or non-invasively for patients with more advanced needs who require round-the-clock therapy.

  • QuickConnectTM single valve circuit means fewer connections are required, helping to prevent incorrect setup of the expiratory valve line and the proximal pressure line.
  • Setup Assistant guides staff step-by-step to ensure the device is appropriately set up for each patient.
  • Learn Circuit is offered to determine the resistance and compliance characteristics of the circuit, ensuring accurate therapy is delivered. It also includes a device self-test, where the oxygen cell and expiratory flow sensors are checked and calibrated.
  • Up to 4 therapy programs allow clinicians to pre-set and store programs for patients with treatment requirements that change under particular conditions (e.g. day/night, with/without humidification). This enables quick transitions between therapy settings without manual fine-tuning.
  • Pressure range: 2–50 cmH2O (leak circuit); 0–50 cmH2O (valve circuit).
  • Real-time graphs and monitored values assist therapy assessment and titration.
  • Encourage patient mobility with battery options providing a total of up to 24 hours of run-time (using the internal battery and 2 additional external batteries).
  • Oxygen is entrained at the back of the device, which can take up to 30 L/min.
  • SpO2 and FiO2 monitoring options are also available.

Comfortable masks that fit a wide range of patients

Building on 25 years of innovation, ResMed offers a wide range of mask types and sizes, designed for comfort, lightness and minimal face coverage. We also provide fitting instructions to help patients learn to fit their mask.


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Personalised non-invasive ventilation made easy

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Invasive and non-invasive ventilators designed for versatility

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Portable life support ventilators to enrich life

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Comfortable masks that fit a wide range of patients


PC-based clinical analysis and patient data management software



Mulqueeny Q et al. Automated detection of asynchrony in patient-ventilator interaction. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:5324-7.


Epstein SK. How often does the patient–ventilator asynchrony occur and what are the consequences? Respir Care. 2011;56(1):25-38.


* World Health Organization. “Chronic respiratory diseases: Burden of COPD” (accessed November 9, 2015)